I realized that they released an exclusive minifigure of The Amazing Spider-Man 2 in the San Diego Comic Con but I am still wondering if they will ever make LEGO set(s) based on the movie.
It depends on licensing as well. Note that they have made sets for Ultimate Spiderman. The X-Men designs all follow their comic counterparts. Loki, Thor etc follow their Movie style counterparts.
This suggests that they have the license for the comic and animated styles, but Fox and Sony retain the rights for the movie looks of the characters.